US Patent Issued to STEMBIOSYS on Oct. 28 for "Methods for the maturation of cardiomyocytes on amniotic fluid cell-derived ECM, cellular constructs, and uses for cardiotoxicity and proarrhythmic screening of drug compounds" (Texas, Michigan Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,677, issued on Oct. 28, was assigned to STEMBIOSYS INC. (San Antonio).

"Methods for the maturation of cardiomyocytes on amniotic fluid cell-derived ECM, cellular constructs, and uses for cardiotoxicity and proarrhythmic screening of drug compounds" was invented by Travis Block (San Antonio), Edward S. Griffey (San Antonio) and Todd Herron (New Hudson, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods of using a cell-derived extracellular matrix derived in-vitro from cells isolated from amniotic fluid (AFC-ECM) for the maturation of immature cardiomyocytes derived from human induced pluripotent stem cells (immature hiPSC-CMs)...