ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,893, issued on Feb. 3, was assigned to STANDARD BIOTOOLS CANADA INC. (Ontario, Canada).

"Mass cytometry reagents and methods for signal amplification" was invented by Bedilu Allo (Whitby, Canada), Xudong Lou (Richmond Hill, Canada), Peng Liu (Markham, Canada), Daniel Majonis (North York, Canada), Anastasia Mavropoulos (Daly City, Canada) and Ladan Gheiratmand (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are reagents and methods for improving signal in imaging mass cytometry. Aspects include mass tags with a large number of labeling atoms, chemical modifications to mass tags and additional reagents to reduce background and/...