ALEXANDRIA, Va., July 30 -- United States Patent no. 12,372,526, issued on July 29, was assigned to St. Jude Children's Research Hospital (Memphis, Tenn.).
"Method for identifying modulators of G3BP activity" was invented by J. Paul Taylor (Memphis, Tenn.), Peiguo Yang (Memphis, Tenn.), Wenwei Lin (Memphis, Tenn.) and Taosheng Chen (Memphis, Tenn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of identifying a lead or candidate compound that modulates the activity of GTPase-Activating Protein SH3 Domain-Binding Proteins (G3BP) is provided, which includes determining whether a compound modulates the interaction between the N-terminal Nuclear Transport Factor 2-like (NTF2L) domain of G3BP and FGDF pep...