US Patent Issued to ST. JUDE CHILDREN'S RESEARCH HOSPITAL, Baylor College of Medicine on Oct. 21 for "Chimeric antigen receptors with MYD88 and CD40 costimulatory domains" (Tennessee Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,426, issued on Oct. 21, was assigned to ST. JUDE CHILDREN'S RESEARCH HOSPITAL INC. (Memphis, Tenn.) and Baylor College of Medicine (Houston).

"Chimeric antigen receptors with MYD88 and CD40 costimulatory domains" was invented by Stephen Gottschalk (Memphis, Tenn.), Brooke Prinzing (Memphis, Tenn.) and Giedre Krenciute (Memphis, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The application relates to a chimeric antigen receptor that targets Eph receptors and allows activation of co-stimulatory pathways. The application also relates to polynucleotides that encode the chimeric antigen receptor, vectors, and host cells comprising the chimeric ant...