ALEXANDRIA, Va., March 12 -- United States Patent no. 12,247,012, issued on March 11, was assigned to SPRINGWORKS THERAPEUTICS INC. (Stamford, Conn.).
"Synthesis of nirogacestat" was invented by Kristin Patterson (Stamford, Conn.) and Mark Hatcher (Stamford, Conn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosures are directed to processes for synthesizing (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide ("nirogacestat")."
The patent was filed on Sept. 30, 2022, under Application No. 17/937,283.
*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/ne...