US Patent Issued to SPECIFIC BIOLOGICS on May 27 for "Lipid-encapsulated dual-cleaving endonuclease for DNA and gene editing" (Canadian Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,615, issued on May 27, was assigned to SPECIFIC BIOLOGICS INC. (Toronto).

"Lipid-encapsulated dual-cleaving endonuclease for DNA and gene editing" was invented by David R. Edgell (London, Canada), Thomas A. McMurrough (London, Canada), Brent E. Stead (Toronto) and Odisho K. Israel (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are modified Staphylococcus aureus Cas9 nucleases and methods of using modified Staphylococcus aureus Cas9 nucleases. Also provided herein are chimeric nucleases comprising an I-Tevl nuclease domain, and a Staphylococcus aureus Cas9 and methods of using the chimeric nuclease. Also provided herein are m...