US Patent Issued to SPARK THERAPEUTICS on Sept. 2 for "Enhancing agents for improved cell transfection and/or rAAV vector production" (New Jersey, Pennsylvania Inventors)

ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,526, issued on Sept. 2, was assigned to SPARK THERAPEUTICS INC. (Philadelphia).

"Enhancing agents for improved cell transfection and/or rAAV vector production" was invented by Guang Qu (Sicklerville, N.J.), Lin Lu (Wayne, Pa.), Jesusa Josue-Almqvist (Havertown, Pa.) and John Fraser Wright (Princeton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compositions and methods of transducing/transfecting cells with a molecule, such as a nucleic acid (e.g., plasmid), at high efficiency. High efficiency transduced/transfected cells can, when transduced with a nucleic acid that encodes a protein or comprises a sequence that is transcribed i...