US Patent Issued to SORRISO PHARMACEUTICALS on Feb. 25 for "Peptide construct having a protease-cleavable linker" (British Inventors)

ALEXANDRIA, Va., Feb. 26 -- United States Patent no. 12,234,279, issued on Feb. 25, was assigned to SORRISO PHARMACEUTICALS INC. (San Diego).

"Peptide construct having a protease-cleavable linker" was invented by Scott Crowe (Babraham, Great Britain), Mike West (Babraham, Great Britain) and Kevin Roberts (Babraham, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "There is provided inter alia a construct suitable for oral administration comprising a first polypeptide and a second polypeptide connected by a labile peptide linker, wherein the labile peptide linker is labile to one or more proteases present in the intestinal tract and wherein the first and second polypeptides are substantially resist...