ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,422,443, issued on Sept. 23, was assigned to SOOCHOW UNIVERSITY (Suzhou, China).
"Amino-substituted chromenoquinoline-based fluorescent marker, and preparation and use thereof" was invented by Jianfeng Ge (Suzhou, China), Mingsen Zhu (Suzhou, China), Qing Yu (Suzhou, China) and Ru Sun (Suzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides an amino-substituted chromenoquinoline-based fluorescent marker, and preparation and use thereof. The amino group of an aromatic amine compound is subjected to a one-step cyclization reaction with two o-chloroformylcumarins, to obtain a series of nitrogen-containing heterocyclic compound....