US Patent Issued to SOOCHOW UNIVERSITY on Nov. 25 for "H 2 O 2 -responsive crosslinking near-infrared molecular probe for tumor microenvironment and use therefor" (Chinese Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,694, issued on Nov. 25, was assigned to SOOCHOW UNIVERSITY (Suzhou, China).

"H 2 O 2 -responsive crosslinking near-infrared molecular probe for tumor microenvironment and use therefor" was invented by Haibin Shi (Suzhou, China) and Yinjia Gao (Suzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention discloses H2O2 responsive crosslinking NIR molecular probe for tumor microenvironment and application therefor. The preparation method includes the following steps: the amide condensation of 2-propynylamine and Fmoc-Lys(Boc)-OH to obtain compound A01-01; removing protecting groups from compound A01-01, to obtain compound C1-2; r...