ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,390,437, issued on Aug. 19, was assigned to Sitryx Therapeutics Ltd. (Oxford, Great Britain).

"Itaconic acid derivatives and uses thereof intreating an inflammatory disease or a disease associated with an undesirable immune response" was invented by Michael Liam Cooke (Nottingham, Great Britain), David Cousin (Nottingham, Great Britain), Matthew Colin Thor Fyfe (Oxfordshire, Great Britain), Barry John Teobald (Oxfordshire, Great Britain), Stephen Malcolm Thom (Nottingham, Great Britain) and Thomas Michael Waugh (Nottingham, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to compounds of formula (IW-1) and to their use ...