US Patent Issued to SIRONAX on Oct. 28 for "Piperazine cyclic ureas" (Chinese, American Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,529, issued on Oct. 28, was assigned to SIRONAX LTD. (Grand Cayman, Cayman Islands).

"Piperazine cyclic ureas" was invented by Yaning Su (Beijing), Zhaolan Zhang (Beijing), Zhiyuan Zhang (San Diego) and Yanping Xu (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are piperazine cyclic urea compounds that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), pharmaceutically acceptable salts, hydrates and stereoisomers thereof. Provided are also pharmaceutical compositions, methods of making, and methods of use which include treating a person in need thereof with an effective amount of the compound or com...