ALEXANDRIA, Va., March 5 -- United States Patent no. 12,241,898, issued on March 4, was assigned to SIRIGEN II Ltd. (Oxford, Great Britain).

"Reagents for directed biomarker signal amplification" was invented by Brent S. Gaylord (San Diego), Glenn P. Bartholomew (Escondido, Calif.), Russell A. Baldocchi (Encinitas, Calif.), Janice W. Hong (San Diego), William H. Huisman (San Diego), Yongchao Liang (Irvine, Calif.), Trung Nguyen (San Diego), Lan T. Tran (Oceanside, Calif.), Jean M. Wheeler (San Diego), Adrian Charles Vernon Palmer (Brighton, Great Britain) and Frank Peter Uckert (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods, compositions and articles of manufacture inv...