ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,911, issued on Nov. 25, was assigned to SinoCellTech Ltd. (Beijing).
"Humanized anti-VEGF antibody Fab fragment" was invented by Liangzhi Xie (Beijing), Chunyun Sun (Beijing), Jun Zhao (Beijing) and Desheng Kong (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention belongs to the field of tumor immunotherapy, and relates to a humanized anti-VEGF antibody Fab fragment. The present invention discloses nucleic acid sequences (including heavy/light chain variable regions) encoding said antibody fragment, and vectors, pharmaceutical compositions and kits containing said nucleic acid sequences. The anti-VEGF antibody Fab fragments ...