US Patent Issued to Sigma-Aldrich on May 13 for "Engineered CAS9 systems for eukaryotic genome modification" (Missouri, California Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,449, issued on May 13, was assigned to Sigma-Aldrich Co. LLC (St. Louis).

"Engineered CAS9 systems for eukaryotic genome modification" was invented by Timothy Seebeck (St. Louis), Fuqiang Chen (St. Louis) and Gregory D. Davis (Berkeley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Engineered Cas9 systems that utilize alternate protospacer adjacent motifs for target DNA binding, nucleic acids encoding the engineered Cas9 systems, and methods of using the engineered Cas9 systems for modifying target chromosomal sequences in eukaryotic cells."

The patent was filed on July 30, 2020, under Application No. 16/943,813.

*For further information, ...