ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,424, issued on Dec. 16, was assigned to SHENZHEN CATALYS TECHNOLOGY Co. LTD (Guangdong, China).

"Chiral multidentate ligand, and application thereof in asymmetric hydrogenation" was invented by Qiwei Lang (Shenzhen, China), Xiaobing Ding (Shenzhen, China) and Yang Xiao (Shenzhen, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a chiral multidentate ligand (I), a preparation, and an application thereof. In this method, compound (M1) is subjected to condensation with compound (M2) followed by amine deprotection in the presence of a deprotection reagent to obtain compound (M4). Compound (1) is subjected to deprotonation by butyl lith...