US Patent Issued to SHANGHAI XINGYE PHARMACEUTICAL TECHNOLOGY on May 6 for "Matrine Alpha-ketoamine compounds, preparation method therefor and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., June 10 -- United States Patent no. 12,291,531, issued on May 6, was assigned to SHANGHAI XINGYE PHARMACEUTICAL TECHNOLOGY Co. LTD (Shanghai).

"Matrine Alpha-ketoamine compounds, preparation method therefor and use thereof" was invented by Weibin Song (Shanghai) and Yanhui Liu (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention disclosed a series of novel matrine Alpha-ketoamine derivatives as shown in formula I, which could inhibit the overexpression of TNF-Alpha and/or activate the immune killing function of the NK cells, thus could be used to treat autoimmune diseases, inflammatory diseases, neurodegenerative diseases and tumors mediated by the abnormal levels o...