ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,846, issued on Jan. 13, was assigned to SHANGHAI VITALGEN BIOPHARMA Co. LTD. (Shanghai).
"Adeno-associated virus capsid" was invented by Kai Xu (Shanghai), Jiabao Han (Shanghai), Wei Li (Shanghai), Shin-Shay Tian (Shanghai) and Xiaoping Zhao (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to an AAV capsid having improved liver tissue tropism and stronger exogenous gene expression, and/or improved ability in escaping from neutralizing antibody. The present disclosure further relates to a nucleic acid encoding the AAV capsid, an AAV particle containing the AAV capsid. The present disclosure further relates to a ...