US Patent Issued to SHANGHAI LONGYAO BIOTECHNOLOGY on July 15 for "Universal CAR-T cell and preparation method and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,169, issued on July 15, was assigned to SHANGHAI LONGYAO BIOTECHNOLOGY INC. LTD. (Shanghai).

"Universal CAR-T cell and preparation method and use thereof" was invented by Xuanming Yang (Shanghai), Yangxin Fu (Shanghai), Xin Wang (Shanghai), Shengqin Ye (Shanghai) and Xiaoqing Zhang (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a universal CAR-T cell knocking out one or more of CD3 delta, CD3 gamma, CD3 epsilon and CD3 zeta, and simultaneously introducing the HSV-TK gene. Also disclosed are a method for preparing the above-mentioned CAR-T cell, a preparation comprising the CAR-T cell, and the use of the CAR-T cell."

The pate...