ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,476, issued on Jan. 27, was assigned to Shanghai Haoyuan Medchemexpress Co. Ltd. (Shanghai).

"Intermediate for synthesizing camptothecin derivative, preparation method therefor, and use thereof" was invented by Hong Wei Zhang (Shanghai), Da Ming Zhang (Shanghai), Tao Ma (Shanghai), Qi Wei Zhu (Shanghai), Zhi Guo Zhou (Shanghai), Kui Mei (Shanghai), Bao Fu Zheng (Shanghai), Qiang Gao (Shanghai) and Hai Ling Yuan (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are an intermediate for synthesizing a camptothecin derivative, a preparation method therefor, and the use thereof. An intermediate A can be obtained from 3-fluoro-4-methylanil...