ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,504, issued on Jan. 27, was assigned to SHANGHAI GP BIOTECH Co. LTD. (Shanghai).
"Il-2 mutant protein proliferating immune cells" was invented by Hui Hu (Shanghai) and Ying Zhang (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided in the present invention are an IL-2 mutant protein, a fusion protein or conjugate containing the IL-2 mutant protein, and a pharmaceutical composition containing the IL-2 mutant protein, fusion protein or conjugate. Compared with wild-type IL-2 protein, the IL-2 mutant protein of the present invention eliminates or reduces the affinity for a high-affinity IL-2 receptor and substantially retains the affinity ...