ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,942, issued on June 3, was assigned to SHANGHAI BAO PHARMACEUTICALS Co. LTD. (Shanghai).

"Use of mutant of immunoglobulin degrading enzyme IdeE" was invented by Yanjun Liu (Shanghai), Zheng Wang (Shanghai), Zhen Zhu (Shanghai) and Lin Lu (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are a mutant of an immunoglobulin degrading enzyme IdeE, a protein comprising the mutant, and a use of a composition and a kit in preparation of a drug for reducing the level of IgG in a subject. The mutant has amino acid substitution, N-terminal truncated and/or C-terminal truncated on one or more of positions 8, 10, 24, 59, 97, and 280 of the amino a...