ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,933, issued on July 22, was assigned to Seven Bridges Genomics Inc. (Charlestown, Mass.).
"Systems and methods for epigenetic analysis" was invented by Devin Locke (Medford, Mass.) and Wan-Ping Lee (Somerville, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides systems and methods for determining patterns of modification to a genome of a subject by representing the genome using a graph, such as a directed acyclic graph (DAG) with divergent paths for regions that are potentially subject to modification, profiling segments of the genome for evidence of epigenetic modification, and aligning the profiled segments to the DAG to d...