ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,552,757, issued on Feb. 17, was assigned to SENJU PHARMACEUTICAL Co. LTD. (Osaka, Japan).
"NRF2-activating compound" was invented by Tomoyo Miyabe (Osaka, Japan), Shinnosuke Machida (Osaka, Japan) and Yuka Oba (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A compound having Nrf2-activating action is provided. The compound is represented by formula (I), a salt of the compound, or a solvate of the compound or salt:wherein R1a and R1b are identical or different and represent a hydrogen atom, an alkyl group, or a halogen atom; R2 represents an optionally substituted group derived from a heterocycle, and the heterocycle represents thiophene, fu...