ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,484, issued on Dec. 23, was assigned to Seismic Pharmaceuticals (Warrington, Pa.).

"Androstane derivatives with activity as pure or predominantly pure stimulators of SERCA2a for the treatment of heart failure" was invented by Alberto Cerri (Milan), Patrizia Ferrari (Varese, Italy), Mara Ferrandi (Milan), Paolo Barassi (Castelvaccana, Italy), Giusseppe Bianchi (Milan), Shih-Che Hsu (Taipai, Taiwan), Francesco Peri (Milan), Antonio Zaza (Milan), Marcella Rocchetti (Brugherio, Italy), Andrea Luraghi (Cerrro Maggiore, Italy), Eleonora Torre (Desio, Italy) and Carlotta Ronchi (Milan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds and composition...