ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,394,503, issued on Aug. 19, was assigned to SEEGENE INC. (Seoul, South Korea).
"Method for predicting the melting temperature of oligonucleotide" was invented by Mi Hyun Jang (Seoul, South Korea), Han Bit Lee (Seoul, South Korea) and Young Jo Lee (Seoul, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for predicting the melting temperature (Tm) of an oligonucleotide, in particular a primer or probe, in a PCR or hybridization assay. The method of present invention can accurately predict the Tm of an oligonucleotide in various reaction environments using the equations for Tm calculation, the equation in...