US Patent Issued to SEATTLE CHILDREN'S RESEARCH INSTITUTE on Aug. 5 for "Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption" (Washington Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,546, issued on Aug. 5, was assigned to SEATTLE CHILDREN'S RESEARCH INSTITUTE (Seattle).

"Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption" was invented by Andrew M. Scharenberg (Seattle), Michael T. Certo (Seattle) and Kamila Sabina Gwiazda (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the polynucleotide ends generated by endonuclease cleavage."

The patent was filed on Dec. 1, 2023, under Application No. 18/526,930.

*For further information, including images...