US Patent Issued to Seattle Children's Hospital on Nov. 11 for "Bispecific chimeric antigen receptors and encoding polynucleotides, vectors and cells thereof" (Washington Inventor)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,466,885, issued on Nov. 11, was assigned to Seattle Children's Hospital (Seattle).

"Bispecific chimeric antigen receptors and encoding polynucleotides, vectors and cells thereof" was invented by Michael Jensen (Bainbridge, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention is directed to a bispecific chimeric antigen receptor, comprising: (a) at least two antigen-specific targeting regions; (b) an extracellular spacer domain; (c) a transmembrane domain; (d) at least one co-stimulatory domain; and (e) an intracellular signaling domain, wherein each antigen-specific targeting region comprises an antigen-specific single chain Fv (scFv) frag...