ALEXANDRIA, Va., April 9 -- United States Patent no. 12,269,844, issued on April 8, was assigned to ScinoPharm Taiwan Ltd. (Tainan, Taiwan).
"Process for purifying semaglutide and liraglutide" was invented by Ming-Chih Wu (Tainan, Taiwan) and Tsung-Yu Hsiao (Tainan, Taiwan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides improved processes for purifying semaglutide or liraglutide. Semaglutide or liraglutide is purified via two sequential RP-HPLC purifications followed by a salt-exchange step, where a pH is kept constant in the first and second purification steps. In particular, the processes utilize a halogenated solvent in a sample preparation step, which provides better solubil...