US Patent Issued to SCINNOHUB PHARMACEUTICAL on Sept. 30 for "Fluorine-containing heterocyclic derivatives with macrocyclic structure and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,433, issued on Sept. 30, was assigned to SCINNOHUB PHARMACEUTICAL Co. LTD (Sichuan, China).

"Fluorine-containing heterocyclic derivatives with macrocyclic structure and use thereof" was invented by Anle Yang (Sichuan, China), Haoxi Huang (Sichuan, China), Tonghui Chen (Sichuan, China), Jie Liang (Sichuan, China), Dewei Zhang (Sichuan, China), Jingen Deng (Sichuan, China), Hongbo Li (Sichuan, China) and Junjie Pu (Sichuan, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a macrocyclic fluorine-containing heterocyclic derivative of formula (I), a preparation method thereof, and a use thereof in treatment of TRK kinase-mediated disea...