ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,688, issued on Nov. 4, was assigned to Scancell Ltd. (Oxford, Great Britain).
"Epitopes" was invented by Wei Xue (Oxfordshire, Great Britain), Katherine Wendy Cook (Oxfordshire, Great Britain), Linda Gillian Durrant (Oxfordshire, Great Britain) and Victoria Anne Brentville (Oxfordshire, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to epitopes containing homocitrulline (Heit) that can be used as targets for cancer immunotherapy. The homocitrullinated T cell epitope has (i) a predicted binding score to MIC class II or class I of greater than30 using the online IEDB prediction program (http://www.iedb.org/) ...