ALEXANDRIA, Va., March 19 -- United States Patent no. 12,253,461, issued on March 18, was assigned to Sartorius Stedim Biotech GMBH (Gottingen, Germany).
"Open-loop/closed-loop process control on the basis of a spectroscopic determination of undetermined substance concentrations" was invented by Marek Hohse (Gottingen, Germany), Alexander Graf (Ulm, Germany) and Christian Grimm (Heiligenstadt, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "Method for open-loop or closed-loop control of a process, in particular a downstream bioprocess, based on the projection of an unknown concentration of at least one substance in a sample using spectroscopy, in particular UV/vis spectroscopy, comprising the steps: D...