ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,607, issued on Jan. 27, was assigned to Sartorius BIA Separations d.o.o. (Ajdovscina, Slovenia).

"Multimodal metal affinity processing AAV capsids" was invented by Maja Leskovec (Ajdovscina, Slovenia), Sara Drmota Prebil (Ajdovscina, Slovenia), Rok Zigon (Ajdovscina, Slovenia), Ales Strancar (Ajdovscina, Slovenia) and Peter S. Gagnon (Las Vegas).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for separating full Adeno-associated virus (AAV) capsids from empty AAV capsids in a buffered mixture comprising full AAV capsids, empty AAV capsids, comprising the steps of contacting the buffered mixture with a first substrate bearing a metal affinity ...