ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,453,782, issued on Oct. 28, was assigned to Sapreme Technologies B.V. (Bilthoven, Netherlands).
"Antibody-oligonucleotide conjugate" was invented by Ruben Postel (Utrecht, Netherlands) and Hendrik Fuchs (Berlin).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a ligand-effector moiety provided with at least one saponin and antibody-effector moiety provided with at least one saponin. An aspect of the invention is a composition comprising the ligand-effector moiety provided with at least one saponin or the antibody-effector moiety provided with at least one saponin of the invention. The invention also relates to an antibody-drug conj...