US Patent Issued to SANOFI PASTEUR on Oct. 28 for "Engineered influenza antigenic polypeptides and immunogenic compositions thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,555, issued on Oct. 28, was assigned to SANOFI PASTEUR INC. (Swiftwater, Pa.).

"Engineered influenza antigenic polypeptides and immunogenic compositions thereof" was invented by Tod Strugnell (Cambridge, Mass.) and Eliud Oloo (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, among other things, a novel and improved method for generating "mosaic" influenza antigenic polypeptides including hemagglutinin (HA) and neuraminidase (NA) polypeptides based on unique combination of epitope patterns that maximize exposure to epitopes present across multiple HA or NA sequences and therefore improved influenza strai...