US Patent Issued to SANOFI on May 13 for "Fc variant with enhanced affinity to Fc receptors and improved thermal stability" (French Inventor)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,273, issued on May 13, was assigned to SANOFI (Paris).

"Fc variant with enhanced affinity to Fc receptors and improved thermal stability" was invented by Alessandro Masiero (Paris).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides Fc domain variants, including effector-competent Fc domain variants. The present disclosure also provides nucleic acids encoding Fc domain variants and host cells for making Fc domain variants. Methods for increasing the yield of Fc domain variants, and methods of using Fc domain variants to treat disease, are also provided."

The patent was filed on May 27, 2022, under Application No. 17/826,29...