ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,715, issued on Feb. 10, was assigned to SAM CHUN DANG PHARM. Co. LTD. (Hwaseong-si, South Korea).
"Refining method of ophthalmic aflibercept" was invented by Byung-Jhip Ha (Yongin-si, South Korea), Yong-Seop Park (Seongnam-si, South Korea), Mee-Ran Seo (Suwon-si, South Korea), Jae-Ho Lee (Suwon-si, South Korea), Dong-Kyu Kim (Suwon-si, South Korea) and Jae-In Jeong (Suwon-si, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for refining an ophthalmic protein pharmaceutical with an isoelectric point in a particular range by applying cation exchange chromatography or anion exchange chromatography. Ac...