US Patent Issued to RULES-BASED MEDICINE on Oct. 14 for "Single domain antibody libraries with maximized antibody developability characteristics" (New Mexico Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,442,107, issued on Oct. 14, was assigned to RULES-BASED MEDICINE INC. (Austin, Texas).

"Single domain antibody libraries with maximized antibody developability characteristics" was invented by Andrew Raymon Morton Bradbury (Santa Fe, N.M.) and Andre A. Teixeira (Santa Fe, N.M.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described here are VHH antibody libraries with heavy chain variable domains framework scaffolds having complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or ...