ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,446, issued on Dec. 30, was assigned to Rottapharm Biotech S.R.L. (Monza, Italy).
"FYN and VEGFR2 kinase inhibitors" was invented by Lucio Claudio Rovati (Monza, Italy), Gianfranco Caselli (Milan), Roberto Artusi (Rho, Italy), Laura Mennuni (Carnate, Italy), Fabrizio Colace (Monza, Italy), Stefano Mandelli (Casatenovo, Italy), Clara Bovino (Gessate, Italy), Filippo Magaraci (Monza, Italy) and Benedetta Buzzi (Meda, Italy).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a N-phenylcarbamoyl compound of Formula (I) or a pharmaceutically acceptable salt thereof for use in the inhibition of at least one of tyrosine kinase selected ...