ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,893, issued on Nov. 25, was assigned to Roche Sequencing Solutions Inc. (Pleasanton, Calif.).
"Site-specific bio-conjugation methods and compositions useful for nanopore systems" was invented by Dmitriy Gremyachinskiy (San Francisco) and Christos Tzitzilonis (Redwood City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to relates methods and associated compositions that provide fast, efficient site-selective conjugation of a protein, such as the pore-forming protein Alpha-hemolysin, to a biomolecule, such as a DNA polymerase, and the use of such site-selective protein-biomolecule conjugates in nanopore devices a...