ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,875, issued on July 8, was assigned to Roche Sequencing Solutions Inc. (Pleasanton, Calif.).
"Detecting cancer driver genes and pathways" was invented by Yao Fu (San Mateo, Calif.), Aparna Chhibber (San Mateo, Calif.), Marghoob Mohiyuddin (Foster City, Calif.), Li Tai Fang (San Francisco) and Hugo Y. K. Lam (Sunnyvale, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods, systems, and apparatuses for detecting significantly mutated genes/pathways in a cancer cohort. A driver gene detection technique taking into account the heterogeneous mutational context in a cancer cohort is disclosed. A statistical model of a gene-spe...