US Patent Issued to Roche Sequencing Solutions on Aug. 5 for "Alpha-hemolysin variants and uses thereof" (California Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,604, issued on Aug. 5, was assigned to Roche Sequencing Solutions Inc. (Pleasanton, Calif.).

"Alpha-hemolysin variants and uses thereof" was invented by Timothy K. Craig (Campbell, Calif.), Mark R. Ambroso (San Jose, Calif.), Corissa J. Harris (Santa Clara, Calif.), Matthew M. Dipietro (Gilroy, Calif.), Yaozhong Zou (Sunnyvale, Calif.) and Marshall W. Porter (Santa Clara, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are variants of alpha-hemolysin having at least one mutation, such as a mutation to a positive charge. In certain examples, the mutation is selected from V149K, E287R, H35G, T109K, P151K, K147N, E111N, M113A, or ...