US Patent Issued to ROCHE INNOVATION CENTER COPENHAGEN on Sept. 23 for "Antisense oligomers targeting PCSK9" (Danish Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,516, issued on Sept. 23, was assigned to ROCHE INNOVATION CENTER COPENHAGEN A/S (Horsholm, Denmark).

"Antisense oligomers targeting PCSK9" was invented by Nanna Albaek (Horsholm, Denmark), Maj Hedtjarn (Horsholm, Denmark), Marie Wickstrom Lindholm (Horsholm, Denmark), Niels Fisker Nielsen (Horsholm, Denmark), Andreas Petri (Horsholm, Denmark) and Jacob Ravn (Horsholm, Denmark).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to oligomeric compounds and conjugates thereof that target Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) PCSK9 mRNA in a cell, leading to reduced expression of PCSK9. Reduction of PCSK9 expres...