ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,461,113, issued on Nov. 4, was assigned to Roche Diagnostics Operations Inc. (Indianapolis).
"IGFBP7 ratio for HFpEF" was invented by Kai Habben (Mannheim, Germany), Vinzent Rolny (Penzberg, Germany), Anika Mang (Mannheim, Germany), Ursula-Henrike Wienhues-Thelen (Penzberg, Germany) and Serge Masson (Rotkreuz, Switzerland).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for differentiating between heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) in a subject suffering from heart failure, said method comprising the steps of determining the amounts of IGF...