ALEXANDRIA, Va., June 16 -- United States Patent no. 12,306,185, issued on May 20, was assigned to Roche Diagnostics Operations Inc. (Indianapolis).

"Detection of anti-p53 antibodies" was invented by Herbert Andres (Penzberg, Germany), Johann Karl (Peissenberg, Germany), Ursula Kunert (Munich), David Morgenstern (Indianapolis), Nina Meissler (Huglfing, Germany), Marion Niessner (Penzberg, Germany) and Magdalena Swiatek-de Lange (Penzberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "An in vitro method is disclosed for detecting an antibody to p53 (anti-p53 antibody) in a sample, the method comprising: incubating a sample to be analyzed with a p53 capture antigen and a p53 detection antigen, whereby...