US Patent Issued to Roche Diagnostics Operations on Feb. 25 for "Mutant reverse transcriptase with increased thermal stability as well as products, methods and uses involving the same" (Japanese, German, Swiss Inventors)

ALEXANDRIA, Va., Feb. 26 -- United States Patent no. 12,234,488, issued on Feb. 25, was assigned to Roche Diagnostics Operations Inc. (Indianapolis).

"Mutant reverse transcriptase with increased thermal stability as well as products, methods and uses involving the same" was invented by Christian Helmut Bell (Basel, Switzerland), Harald Sobek (Biberach, Germany), Heiko Walch (Munich), Kiyoshi Yasukawa (Koyoto, Japan) and Misato Baba (Hyto, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a mutant reverse transcriptase (RT) with increased thermal stability relative to the wildtype, a nucleic acid encoding the mutant RT, a cell comprising the mutant RT or the nucleic acid, a...