US Patent Issued to RIKEN on Feb. 10 for "Mitochondrial permeability transition pore (mPTP)-opening inhibitor, novel compound exhibiting mPTP-opening inhibitory activity, and use therefor" (Japanese Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,354, issued on Feb. 10, was assigned to RIKEN (Wako, Japan).

"Mitochondrial permeability transition pore (mPTP)-opening inhibitor, novel compound exhibiting mPTP-opening inhibitory activity, and use therefor" was invented by Tadafumi Kato (Wako, Japan), Mie Sakashita (Wako, Japan), Hirochika Kawakami (Wako, Japan), Ko Kikuzato (Wako, Japan) and Fumiyuki Shirai (Wako, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention aims to provide a novel compound having a high mPTP-opening inhibitory activity and/or a useful therapeutic effect on various diseases. An aspect of the present invention relates to a mitochondrial permeability t...