ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,433, issued on Dec. 16, was assigned to RIKEN (Saitama, Japan).
"Fluorescent protein and utilization thereof" was invented by Yusuke Niino (Saitama, Japan) and Atsushi Miyawaki (Saitama, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A fluorescent protein of the present invention has an amino acid sequence of a green fluorescent protein (GFP) derived from a crystal jelly or of a mutant fluorescent protein of the green fluorescent protein, the amino acid sequence having an amino acid residue (alanine residue) substituted with a phenylalanine residue, the amino acid residue corresponding to position 206 with the amino acid sequence of the GFP us...