ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,687, issued on April 15, was assigned to RIKEN (Wako, Japan).
"Class a GPCR-binding compound modifier" was invented by Shigeyuki Yokoyama (Yokohama, Japan) and Tetsuya Hori (Yokohama, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "To provide a novel class-A GPCR antagonist, a production method therefor, or a novel compound that interacts with a Na+-water cluster binding site of a class-A GPCR.Used is a compound or a salt thereof comprising a structure comprising a class-A GPCR-binding compound linked to a functional group that can bind to a Na+-water cluster binding site of the class-A GPCR. Also used is a method for producing a class-A GPCR an...