ALEXANDRIA, Va., June 9 -- United States Patent no. 12,285,543, issued on April 29, was assigned to RIKEN (Wako, Japan) and Sumitomo Pharma Co. Ltd. (Osaka, Japan).
"Human cell population comprising human retinal progenitor cells without an ISL1 gene for transplantation and methods of use thereof" was invented by Michiko Mandai (Wako, Japan), Masayo Takahashi (Wako, Japan) and Suguru Yamasaki (Kobe, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "An object of the present invention is to provide a cell population suitable for transplant of retinal tissue and a method of production thereof. The present invention provides a cell population for transplant, comprising retinal cells with a modified bipolar ce...